Pediatric Airway Analysis

We are designing analysis methods to capture normal growth of pediatric airways (to build a pediatric airway atlas). This project is also concerned with predicting growth for individuals. The driving problem is airway obstruction in children (such as Pierre Robin sequence or subglottic stenosis) which can either be treated by “watch-and-wait” or surgery. The goals are 1) to provide feedback to a surgeon with respect to potential outcomes, 2) to assess achieved surgical outcome (i.e., how does a child’s airway compare to a normal control population before and after surgery), and 3) to ultimately evaluate the necessity of surgical interventions for individual children. We have developed approaches to build airway atlases ( [hong14] [hong13a] [hong13b] ) and have applied these approaches to analyze airways in infants and children with subglotic stenosis ( [zdanski05] ).


Statistical atlas construction via weighted functional boxplots

Atlas-building from population data is widely used in medical imaging. However, the emphasis of atlas-building approaches is typically …

A pediatric airway atlas and its application in subglottic stenosis

Young children with upper airway problems are at risk for hypoxia, respiratory insufficiency and long term morbidity. Computational …

Quantitative assessment of the upper airway in infants and children with subglottic stenosis

OBJECTIVES: Determine whether geometric measures and computational fluid dynamic modeling (CFD) derived from medical imaging are …

Marc Niethammer
Marc Niethammer
Professor of Computer Science

My research interests include image registration, image segmentation, shape analysis, machine learning, and biomedical applications.