Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that features of …
The average diffusion propagator (ADP) obtained from diffusion MRI (dMRI) data encapsulates important structural properties of the underlying tissue. Measures derived from the ADP can be potentially used as markers of tissue integrity in …
This paper proposes a new method to compute connectivity information from diffusion weighted images. It is inspired by graph-based approaches to connectivity definition, but formulates the estimation problem in the continuum. In particular, it …
Existing atlas-building methods for di usion-tensor images are not designed for longitudinal data. This paper proposes a novel longitudinal atlas-building framework explicitly accounting for temporal dependencies of longitudinal MRI data. …
This paper describes a method for model-based averaging of sets of diffusion weighted magnetic resonance images (DW-MRI) under space transformations (resulting for example from registration methods). A robust weighted least squares method is …
This paper presents a novel method of optimizing point-based correspondence among populations of human cortical surfaces by combining structural cues with probabilistic connectivity maps. The proposed method establishes a tradeoff between an even …
MR diffusion tensor imaging (DTI) can measure and visualize organization of white matter fibre tracts in vivo. DTI is a relatively new imaging technique, and new tools developed for quantifying fibre tracts require evaluation. The purpose of this …
This paper introduces and analyzes a linear minimum mean square error (LMMSE) estimator using a Rician noise model and its recursive version (RLMMSE) for the restoration of diffusion weighted images. A method to estimate the noise level based on …
This work provides a framework for modeling and extracting the Cingulum Bundle (CB) from Diffusion-Weighted Imagery (DW-MRI) of the brain. The CB is a tube-like structure in the brain that is of potentially of tremendous importance to clinicians …
In this paper, we present a novel approach for the segmentation of white matter tracts based on Finsler active contours. This technique provides an optimal measure of connectivity, explicitly segments the connecting fiber bundle, and is equipped with …