We introduce an end-to-end deep-learning framework for 3D medical image registration. In contrast to existing approaches, our framework combines two registration methods: an affine registration and a vector momentum-parameterized stationary velocity …
We introduce a region-specific diffeomorphic metric mapping (RDMM) registration approach. RDMM is non-parametric, estimating spatio-temporal velocity fields which parameterize the sought-for spatial transformation. Regularization of these velocity …
The plethora of data from neuroimaging studies provide a rich opportunity to discover effects and generate hypotheses through exploratory data analysis. Brain pathologies often manifest in changes in shape along with deterioration and alteration of …
Registering brain magnetic resonance imaging (MRI) scans containing pathologies is challenging primarily due to large deformations caused by the pathologies, leading to missing correspondences between scans. However, the registration task is …
Mapping images into the same anatomical coordinate system via image registration is a fundamental step when studying physiological processes, such as brain development. Standard registration methods are applicable when biological structures are …
Registration involving one or more images containing pathologies is challenging, as standard image similarity measures and spatial transforms cannot account for common changes due to pathologies. Low-rank/Sparse (LRS) decomposition removes …
We introduce a deep encoder-decoder architecture for image deformation prediction from multimodal images. Specifically, we design an image-patch-based deep network that jointly (i) learns an image similarity measure and (ii) the relationship between …
Analyzing large-scale imaging studies with thousands of images is computationally expensive. To assess localized morphological differences, deformable image registration is a key tool. However, as registrations are costly to compute, large-scale …
Elastic physical models have been widely used to regularize deformations in different medical object registration tasks. Traditional approaches usually assume uniform isotropic tissue elasticity (a constant regularization weight) across the whole …
This paper presents a novel mathematical framework for representing uncertainty in large deformation diffeomorphic image registration. The Bayesian posterior distribution over the deformations aligning a moving and a fixed image is approximated via a …