brain

Robust estimation of group-wise cortical correspondence with an application to macaque and human neuroimaging studies

We present a novel group-wise registration method for cortical correspondence for local cortical thickness analysis in human and non-human primate neuroimaging studies. The proposed method is based on our earlier template based registration that …

Shape analysis based on depth-ordering

In this paper we propose a new method for shape analysis based on the ordering of shapes using band-depth. We use this band-depth to non-parametrically define a global depth for a shape with respect to a reference population, typically consisting of …

Splines for diffeomorphisms

This paper develops a method for higher order parametric regression on diffeomorphisms for image regression. We present a principled way to define curves with nonzero acceleration and nonzero jerk. This work extends methods based on geodesics which …

Uncertainty Quantification for LDDMM Using a Low-Rank Hessian Approximation

This paper presents an approach to estimate the uncertainty of registration parameters for the large displacement diffeomorphic metric mapping (LDDMM) registration framework. Assuming a local multivariate Gaussian distribution as an approximation for …

Depth-Based Shape-Analysis

In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to non-parametrically define depth with respect to a normal control population. This allows us to quantify differences with …

Large deformation diffeomorphic registration of diffusion-weighted imaging data

We seek to compute a diffeomorphic map between a pair of diffusion-weighted images under large deformation. Unlike existing techniques, our method allows any diffusion model to be fitted after registration for subsequent multifaceted analysis. This …

Low-Rank to the Rescue - Atlas-Based Analyses in the Presence of Pathologies

Low-rank image decomposition has the potential to address a broad range of challenges that routinely occur in clinical practice. Its novelty and utility in the context of atlas-based analysis stems from its ability to handle images containing large …

PORTR: Pre-Operative and Post-Recurrence Brain Tumor Registration

We propose a new method for deformable registration of pre-operative and post-recurrence brain MR scans of glioma patients. Performing this type of intra-subject registration is challenging as tumor, resection, recurrence, and edema cause large …

Time-Warped Geodesic Regression

We consider geodesic regression with parametric time-warps. This allows, for example, to capture saturation effects as typically observed during brain development or degeneration. While highly-flexible models to analyze time-varying image and shape …

Cortical correspondence via sulcal curve-constrained spherical registration with application to Macaque studies

In this work, we present a novel cortical correspondence method with application to the macaque brain. The correspondence method is based on sulcal curve constraints on a spherical deformable registration using spherical harmonics to parameterize the …