knee

Osteoarthritis

Image analysis approaches for the quantitative analysis of osteoarthritis in the knee.

Adversarial Data Augmentation via Deformation Statistics

Deep learning models have been successful in computer vision and medical image analysis. However, training these models frequently requires large labeled image sets whose creation is often very time and labor intensive, for example, in the context of …

Anatomical Data Augmentation via Fluid-based Image Registration

We introduce a fluid-based image augmentation method for medical image analysis. In contrast to existing methods, our framework generates anatomically meaningful images via interpolation from the geodesic subspace underlying given samples. Our …

DeepAtlas: Joint Semi-supervised Learning of Image Registration and Segmentation

Deep convolutional neural networks (CNNs) are state-of-theart for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor intensive. …

Networks for Joint Affine and Non-Parametric Image Registration

We introduce an end-to-end deep-learning framework for 3D medical image registration. In contrast to existing approaches, our framework combines two registration methods: an affine registration and a vector momentum-parameterized stationary velocity …

Region-specific Diffeomorphic Metric Mapping

We introduce a region-specific diffeomorphic metric mapping (RDMM) registration approach. RDMM is non-parametric, estimating spatio-temporal velocity fields which parameterize the sought-for spatial transformation. Regularization of these velocity …

Contextual Additive Networks to Efficiently Boost 3D Image Segmentations

Semantic segmentation for 3D medical images is an important task for medical image analysis which would benefit from more efficient approaches. We propose a 3D segmentation framework of cascaded fully convolutional networks (FCNs) with contextual …

Diseased Region Detection of Longitudinal Knee Magnetic Resonance Imaging Data

Magnetic resonance imaging (MRI) has become an important imaging technique for quantifying the spatial location and magnitude/direction of longitudinal cartilage morphology changes in patients with osteoarthritis (OA). Although several analytical …

Automatic atlas-based three-label cartilage segmentation from MR knee images

Osteoarthritis (OA) is the most common form of joint disease and often characterized by cartilage changes. Accurate quantitative methods are needed to rapidly screen large image databases to assess changes in cartilage morphology. We therefore …

Automatic localized analysis of longitudinal cartilage changes

Osteoarthritis (OA) is the most common form of arthritis; it is characterized by the loss of cartilage. Automatic quantitative methods are needed to screen large image databases to assess changes in cartilage morphology. This dissertation presents an …