Topology

We have developed various analysis approaches based on topology. Our early work explored using topological descriptors for shape analysis ( [mischaikow02] [niethammer06] ). We have also explored using topology to characterize cell arrangements in the context of breast cancer ( [singh14] ) and as general shape descriptors ( [hofer17b] ). Another focus has been how to combine persistence diagrams with machine learning, in a kernel setting ( [kwitt15] ) as well as using deep learning ( [hofer17a] [hofer19b] ). As persistence diagrams require the definition of a filtration we have explored learning the corresponding filter function as well ( [hofer20b] ). Most recently we have explored how to use topology to obtain distributions which are beneficial for small-sample learning ( [hofer20a] ).

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Marc Niethammer
Marc Niethammer
Professor of Computer Science

My research interests include image registration, image segmentation, shape analysis, machine learning, and biomedical applications.

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